The Northview Journal

Medication-Assisted Treatment

What Are the Benefits of Sublocade for Opioid Addiction Treatment?

A clinical look at the FDA-approved monthly buprenorphine injection — what it does in the brain, the withdrawal symptoms it eases, and how it’s administered.

A medication vial on a clean clinical surface — suggestive of Sublocade treatment

Benefits at a glance

Benefit 01 Blocks the “drug-liking” effect at mu opioid receptors
Benefit 02 Eases common opioid withdrawal symptoms
Benefit 03 Once-monthly extended-release injection
Benefit 04 FDA-approved (2017) for opioid use disorder

The landscape

The numbers surrounding opioid use in the United States are alarming — 2.1 million people have an opioid use disorder and 8–12% of this number started out innocently enough with prescription painkillers. Once an opioid use disorder takes hold, the disease is extraordinarily tough to beat as it hijacks your mental, emotional, and physical health.

At Northview Wellness Practice, our team of addiction specialists understands the seemingly impenetrable prison that an opioid use disorder creates, which is why we offer the latest treatments for breaking the chains of addiction and dependency. One of the more recent treatments approved by the FDA in 2017 is showing great promise in helping ease the road to recovery —Sublocade.

Here’s a look at the benefits of using Sublocade to treat opioid addiction.

Section 01

The makings of an opioid use disorder

Before we get into how Sublocade works, it’s helpful to take a step back and review exactly what happens to someone who takes opioids. As painkillers, opioids do their job well by attaching themselves to specific receptors in your brain and nervous system to block pain. At the same time, the opioids also create a euphoric effect, which activates the pleasure and reward centers in your brain — and therein lies the problem.

As you continue to take opioids, your brain “rewires” itself to receive more of the pleasurable side effects, creating new neural pathways that override all else. This, in turn, leads to uncontrollable cravings and the inability to quit, which are two of the primary hallmarks of addiction.

At the same time, your body comes to physically rely on the drug, which is where the dependency component comes in and wreaks havoc. Quitting opioid use often comes with extremely unpleasant side effects, such as anxiety, nausea, and body aches, and these withdrawal symptoms throw up very large hurdles on the road to quitting.

Section 02

Sublocade — blocking the addiction

The main ingredient in Sublocade is buprenorphine, which is a partial agonist at the mu opioid receptors in your brain. The mu opioid receptors are responsible for many of the subjective side effects of opioids, including “drug-liking.”

With Sublocade, we essentially block your brain from receiving the pleasurable side effects it’s come to count on by blocking the opioids from attaching to your mu opioid receptors.

While the above is more of a scientific explanation, the main takeaway is that Sublocade works to prevent your brain from succumbing to the effects of the opioids, halting the rewiring that happens when you take the drug and allowing your brain to operate with more “normal” neural pathways.

Just as important, Sublocade works to offset some of the more common symptoms of opioid withdrawal, including:

Symptoms Sublocade addresses

  • Nausea or vomiting
  • Body aches
  • Fever
  • Diarrhea
  • Depression and anxiety

By addressing these withdrawal symptoms, Sublocade breaks down the hurdles to quitting, smoothing your way forward.

Section 03

Taking Sublocade

Sublocade is an extended-release injection that we administer once a month. We typically start you with a sublingual version of buprenorphine, which you take for seven days. After that, we switch you over to the once-monthly Sublocade injection.

Of course, there are many other tools you can use during this time to help you break the chains of addiction, and we’re with you every step of the way.

If you’d like to learn more about the benefits of including Sublocade in your addiction treatment plan, please contact our office by phone, email, or by using the online messaging tool on this website.

Talk With Our Team

Could Sublocade be part of your treatment?

A confidential conversation is the easiest way to find out where the monthly injection might fit — and what the first week of sublingual buprenorphine looks like as a starting point.

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